Larissa (Greek: Λάρισα[ˈlarisa]) is the capital and largest city of the Thessaly region, the fifth-most populous in Greece and capital of the Larissa regional unit. It is a principal agricultural centre and a national transport hub, linked by road and rail with the port of Volos, the cities of Thessaloniki and Athens. Larissa, within its municipality, has 162,591 inhabitants, while the regional unit of Larissa reached a population of 284,325 (in 2011). The urban area of the city, although mostly contained within the Larissa municipality, also includes the communities of Giannouli, Platykampos, Nikaia, Terpsithea and several other suburban settlements, bringing the wider urban area population of the city to about 174,012 inhabitants and extends over an area of 572.3 km2 (221.0 sq mi).
Legend has it that Achilles was born here. Hippocrates, the Father of Medicine, died here. Today, Larissa is an important commercial, agricultural and industrial centre of Greece.